Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd
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Modelo: Acalabrutinib 479
marca: Dm.
99+ Purity: White Crystalline Powder
Pacote: PE duplo com saco de folha de alumínio
transporte: Ocean,Air
Lugar de origem: Hebei, China
Certificados : ISO9001
porta: Shanghai,Beijing,Shenzhen
Tipo de pagamento: L/C,T/T
Incoterm: FOB,CIF
Nome do produto: AcalAbrutinib
CAS NO.1420477-60-6.
Aparência: pó cristalino branco
Putacidade: 99,0% +
Aplicação: API.
A AcalAbrutinib, também conhecida como ACP-196, é um inibidor oralmente disponível da tirosina quinase (BTK) de Bruton com potencial atividade antineoplásica. Após a administração, a ACP-196 inibe a atividade da BTK e impede a ativação do caminho de sinalização do receptor de antígeno B-célula (BCR). Isso impede tanto a ativação da célula B quanto a ativação mediada pela BTK das vias de sobrevivência a jusante. Isso leva a uma inibição do crescimento de células B malignas que superexpressam o BTK. BTK, membro da família BTK / TEC relacionada à SRC de cinanases citoplasmáticas de tirosina, é superexpressada em malignidades de células B; Joga um papel importante no desenvolvimento de linfócitos B, ativação, sinalização, proliferação e sobrevivência.
Produtos Principais:
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ACALABRUTINIB阿卡拉替尼1420477-60-6 |
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1-pyrrolidinecarboxylic acid, 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-, phenylmethyl ester,( 58511960, 57636041,2s)- |
阿卡拉中间体 (s)-苯基 2-(8-氨基-1-溴咪唑[1,5-a]吡嗪-3-基)吡咯烷-1-羧酸酯 |
142078-88-1 |
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4-(pyridin-2-yl)aminocarbonylphenylboronic acid |
阿卡拉中间体 4-(砒啶-2-基)甲酰氨苯基硼酸 |
'850568-25-1 |
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AXITINIB 阿西替尼 319460-85-0 |
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2-mercapto-n-methylbenzamide |
2-巯基-n-甲基苯甲酰胺 |
20054-45-9 |
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6-iodo-1h-indazole |
6-碘-1h-吲唑 |
261953-36-0 |
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BREXPIPRAZOLE 依匹唑哌 913611-97-9 |
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4-bromobenzo[b]thiophene |
4-溴苯并b噻吩 |
5118-13-8 |
7-hydroxyquinolinone |
7-羟基-2-喹诺酮 |
70500-72-0 |
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DANTROLENE SODIUM 丹曲林钠 24868-20-0 |
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DAROLUTAMIDE 多拉米胺 1297538-32-9 |
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ENZALUTAMIDE 恩杂鲁胺 915087-33-1 |
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3-fluoro-4-methylphenylisothiocyanate |
4-异硫代氰酰基-2-(三氟甲基)苯甲腈 |
143782-23-4 |
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4-bromo-2-fluorobenzoic acid |
4-溴-2-氟苯甲酸 |
112704-79-7 |
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N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine methyl ester |
N-[3-氟-4-[(甲基氨基)羰基]苯基]-2-甲基丙氨酸甲酯 |
1332524-01-2 |
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N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-2-methylalanine |
N-[3-氟-4-[(甲基氨基)羰基]苯基]-2-甲基丙氨酸 |
1289942-66-0 |
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LORLATINIB(PF0643922)劳拉替尼1454846-35-5 |
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1-methyl-3-((methylamino)methyl)-1h-pyrazole-5-carbonitrilehydrochloride |
1-甲基-3-（甲氨基）甲基吡唑-5-甲腈盐酸盐
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1643141-20-1 |
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1-methyl-3-((methylamino)methyl)-1h-pyrazole-5-carbonitrile |
1-甲基-3-（甲氨基）甲基吡唑-5-甲腈 |
1454852-76-6 |
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(S)-1-(5-fluoro-2-iodophenyl)ethan-1-ol |
(S)-1-(2-碘-5-氟苯基)乙醇 |
1454847-96-1 |
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Methyl(r)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate |
甲基（R）-2-（1-（（2-氨基-5-溴吡啶-3-氧乙基）-4-氟苯甲酸 |
1454848-00-0 |
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NIRAPARIB TOSYLATE甲苯磺酸尼拉帕尼一水合物1613220-15-7 |
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3-formyl-2-nitrobenzoic acid methyl ester |
3-甲酰基-2-硝基苯甲酸甲酯 |
138229-59-1 |
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tert-butyl (S)-3-(4-bromophenyl)piperidine-1-carboxylate |
尼拉帕尼甲苯磺酸盐 |
1476776-55-2 |
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OLAPARIB 奥拉帕尼 763113-22-0 |
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2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile |
2-氟-5-[(3-氧代-1(3H)-异苯并呋喃甲叉基苯甲腈 |
763114-25-6 |
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3-Cyano-4-fluorobenzaldehyde |
3-氰基-4-氟苯甲醛 |
218301-22-5 |
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SELEXIPAG 赛乐西帕475086-01-2 |
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4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol |
4-[(5,6-二苯基-2-吡嗪基)(1-甲基乙基l)氨基]-1-丁醇 |
475086-75-0 |
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5-chloro-2,3-diphenylpyrazine |
5-氯-2,3-二苯基吡嗪 |
41270-66-0 |
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4-hydroxy-n-isopropylbutan-1-amine |
4-(异丙基氨基)-1-丁醇 |
42042-71-7 |
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SORAFENIB TOSYLATE 甲苯磺酸索拉菲尼 475207-59-1 |
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N-methyl-4-chloropyridine-2-carboxamide |
4-氯-N-甲基烟酰胺 |
220000-87-3 |
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4-chloro-3-(trifluoromethyl)phenyl isocyanate |
4-氯-3-（三氟甲基）苯异氰酸酯 |
327-78-6 |
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SUNITINIB MALATE 苹果酸舒尼替尼 341031-54-7 |
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5-formyl-2,4-dimethyl-1h-pyrrole-3-carboxylic acid |
5-甲酰基-2,4-二甲基吡咯-3-羧酸 |
253870-02-9 |
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5-fluoro-1,3-dihydro-2h-indol-2-one |
5-氟吲哚-2-酮 |
56341-41-4 |
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TEMOZOLOMIDE 替莫唑胺 85622-91-1 |
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4-amino-5-imidazolecarboxamide hydrochloride |
阿卡盐酸盐/4-氨基-5-甲酰胺咪唑盐酸盐 |
72-40-2 |
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5-amino-1h-imidazole-4-carboxamide hydrate |
阿卡一水物/4-氨基-5-甲酰胺咪唑一水物 |
360-97-4 |
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TASIMELTEON他司美琼CAS：609799-22-6 |
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((1R,2R)-2-(2,3-dihydrobenzofuran-4-yl)cyclopropyl)methanamine |
((1R,2R)-2-(2,3-二氢苯并呋喃-4-基)环丙基)甲烷胺 |
1400898-49-8 |
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VENETOCLAX 维奈妥拉 1257044-40-8 |
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5-hydroxy-7-azaindole |
5-羟基-7-氮杂吲哚 |
98549-88-3 |
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Methyl 2-((1h-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4- (4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoate |
2-((1H-吡咯[2,3-b]吡啶-5-基)氧基)-4-(4-((4'-氯-5,5-二甲基-3,4,5,6-四氢-[1,1'-二苯基]-2-基)甲基)哌嗪-1-基) 苯甲酸甲酯 |
1235865-76-5 |
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1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride |
1-((4'-氯-5,5-二甲基-3,4,5,6-四氢-[1,1'-二苯基]-2-基)甲基)哌嗪二盐酸盐 |
1628047-87-9 |
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3-nitro-4-(((tetrahydro-2h-pyran-4-yl)methyl)amino)benzenesulfonamide |
3-硝基-4-(((四氢-2H-吡喃-4-基)甲基)氨基)苯磺酰胺 |
1228779-96-1 |
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TEZACAFTOR (VX661) 1152311-62-0 and All Intermediates |
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2-bromo-5-fluoro-4-nitroaniline |
苯胺,2-溴-5-氟-4-硝基 |
952664-69-6 |
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(((2,2-dimethylbut-3-yn-1-yl)oxy)methyl)benzene |
(((2,2-二甲基-丁-3-炔-1-基)氧基)甲基)苯 |
1092536-54-3 |
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(R)-2-((benzyloxy)methyl)oxirane |
(R)-苄氧甲基环氧乙烷 |
14618-80-5 |
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IVACAFTOR (VX770) 依伐卡托 873054-44-5 |
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4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
4-氧代-1,4-二氢喹啉-3-羧酸 |
13721-01-2 |
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5-amino-2,4-di-tert-butylphenol hydrochloride (base) |
5-氨基-2,4-二叔丁基苯酚 |
873055-58-4 |
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LUMACAFTOR (VX809) 鲁玛卡托 936727-05-8 |
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1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxylic acid |
1-(2,2-二氟苯并[D][1,3]二氧杂环戊烯-5-基)环丙烷甲酸 |
862574-88-7 |
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6-chloro-5-methylpyridin-2-amine |
6-氯-5-甲基-2-吡啶胺 |
442129-37-5 |
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3-boronobenzoic acid |
2-羧基苯硼酸 |
149105-19-1 |
Grupo de Produto : APIs e intermediários > AcalAbrutinib.
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